September 20, 2021


affection for others

Titanium dioxide no longer regarded safe as feed additive

The assessment​ by EFSA’s Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) follows the recent conclusion reached by the authority’s Panel on Food Additives and Flavorings (FAF) that the same compound is not safe when used as a food additive.

The FEEDAP Panel said it could not rule out concerns related to genotoxicity – the ability of a substance to damage DNA, the genetic material of cells.

After oral ingestion, the absorption of titanium dioxide (TiO2) particles is low, but they can accumulate in the body. This, together with the absence of specific data related to its use as a feed additive, the fact that no information on the potential exposure of consumers to TiO2 particles in food products from animals fed the additive is available, the FEEDAP Panel said it could not conclude on the safety of TiO2 for the consumer.

A lack of adequate data to evaluate the safety of TiO2 for the environment, including the impact of the presence of nanoparticles meant the FEEDAP Panel was also unable to determine the safety for the environment of TiO2 when used as a feed additive for all animal species.

Regarding user safety, titanium dioxide is considered potentially carcinogenic by inhalation, found FEEDAP.

Re-evaluation request 

The EU Commission received a request from the company Kronos International for the re-evaluation of titanium dioxide for use as an additive in feedstuffs for all animal species and categories.

The compound was placed on the EU market pursuant to Council Directive 70/524/EEC, being a coloring agent authorized for coloring foodstuffs by Community rules in application of Article 9t (b) of Council Directive 70/524/EEC.  It is authorized for use in food for cats and dogs as colorant additive. The additive is also approved for use in feed for all animal species other than cats and dogs, but it is applied in by-products of the food industry to be used in feed and not as direct use to color the feed.