Top Joint Supplements: Best Joint Health Support Products (2022)

Table of Contents The Best Joint Supplements for 2021PureHealth Research Joint Support PlusBioTrust Joint 33XPhytage…

Aside from heart diseases, inflammation and chronic joint discomfort are other common health problems in the human body. Most tasks that you usually find easy to carry out can become painful and even unbearable with this condition. This type of health issue could make your everyday activities extremely difficult. Because of these issues, joint products have become common in the market.

These supplements are developed to reverse or slow down the pain and inflammation caused by weakened and inflamed joints. Popular joint products consist of three primary ingredients – methylsulfonylmethane (often regarded as MSM), chondroitin, and glucosamine. Studies claim that these three ingredients offer some health benefits to the joints. The ingredients can help to decrease the inflammation caused by swelling and pain.

Joint pain products are standard nowadays, and many are of little or no genuine value, and many of these supplements lack the compounds you need. So you need to be extra careful when choosing the best supplement for your joints.

To make it easy for you, we’ve taken it upon ourselves to take a thorough look at the top 12 joint supplements. Read further to assess our top joint supplements.

The Best Joint Supplements for 2021

The best 2021 joint supplements available online can be a daunting task to assess on your own. Before we compiled this list, we checked out various lab reports, contacted different joint manufacturers to ensure that these products lived up to expectations. After several studies and deliberation, here is a list of the top joint supplements options for you in 2021 & after:

  • PureHealth Research Joint Support Plus
  • BioTrust Joint 33X
  • Phytage Labs Joint Relief 911
  • Organifi Move
  • Zenith Labs Joint N-11
  • VitaPost ProJoint Plus
  • Joint Support + by Nuzena
  • MoveMD by 1MD
  • Universal Nutrition Animal Flex
  • Zenwise Advanced Strength Joint Support
  • Vimerson Health Glucosamine Chondroitin Turmeric MSM & Boswellia
  • Schiff Move Free Joint Health

PureHealth Research Joint Support Plus


The first product on our list is the Joint Support Plus from PureHealth Research. The product uses type II collagen alongside anti-inflammatory herbal extracts to enhance mobility and flexibility. The supplement contains antioxidants like Boswellia, resveratrol, and turmeric to eliminate joint pain caused by inflammation. In addition to these antioxidants, the product includes Bioperine to help improve the bioavailability of the remaining ingredients.

Though the supplement does not include popular ingredients like glucosamine or chondroitin, we think it’s still an excellent joint supplement. The inclusion of collagen is a plus because it helps to stimulate collagen synthesis in the joints. This helps to improve joint strength.

BioTrust Joint 33X


While we recommend any joint supplement that combines the top three ingredients (MSM, glucosamine, and chondroitin), BioTrust took its game to a whole new level. The good news is that BioTrust Joint 33X consists of three patented compounds that can lubricate, repair, and restore your joints.

One of the ingredients is the UC-II, which is a patented kind of type II collagen. It helps to stimulate the growth and repair of cartilage in the joints. In a study, UC-II was three times more productive in improving joint function and reducing joint pain than chondroitin and glucosamine.

Another one is ApresFlex, a patented kind of Boswellia, and it helps prevent joint inflammation by blocking the immune system’s response. In one piece of research, ApresFlex was discovered to decrease joint pain within five days.

The last patented ingredient is Mobilee, a combination of polysaccharides, collagen, and hyaluronic acid. It helps to reinstate synovial fluid and lubricate the joints to decrease friction. Mobilee was found five times more efficient than only hyaluronic acid in a study. These three patented compounds are why BioTrust Joint 33X from BioTrust is among the best joint supplements around.

What’s more, Joint 33X is among the most reliable and trusted manufacturers in the supplement market. Aside from that, they have a great history of well-designed and top-notch supplements that satisfy expectations.

BioTrust Joint 33X is the best option to consider if you want comfort from joint discomfort.

Phytage Labs Joint Relief 911


Joint Relief 911 from Phytage Labs is an advanced supplement that uses Andrographis paniculata – one of the latest herbal extracts. The research discovered that this extract could efficiently block inflammatory signs in the human body to stop the immune system response that can lead to inflammation.

In addition, Phytage Labs Joint Relief 911 consists of hyaluronic acid that can help to reinstate the synovial fluid to lubricate the joints. Though Joint Relief 911 is not a conventional joint supplement, it has outstanding online reviews, and it’s an excellent option if you want to consider something aside from chondroitin.

Organifi Move


Organifi Move is an anti-inflammatory joint support product that contains astaxanthin powder, organic holy basil leaf extract, and turmeric. These four herbal extracts are known to decrease acute inflammation throughout the body.

Unfortunately, the supplement does not include three prominent ingredients (MSM, glucosamine, and chondroitin). So, while it may help decrease inflammation, it may not be an ideal option for directly targeting joint pain itself.

Zenith Labs Joint N-11


Joint N-11 from Zenith is an incredible joint formula that utilizes pure niacinamide as the primary ingredient. Studies discovered that vitamin B3 is vital for joint health, which might help decrease the effect of osteoarthritis. The product uses two unique blends, which can help to remove even the worst joint discomfort and inflammatory issues.

The first blend is the “absorption blend,” It contains ginger root, basil, and BioPerine. These ingredients will help the body absorb niacinamide. The other blend is the “rapid relief blend” consisting of MSM, turmeric, and other potent anti-inflammatory compounds developed to enhance mobility, restore cartilage and decrease swelling.

Although Joint N-11 contains several anti-inflammatory herbal extracts well-known to improve joint health, we’re still cautious that it does not contain chondroitin and glucosamine.

Without chondroitin and glucosamine, we can’t assure that Joint N-11 is powerful enough to prevent people from suffering severe joint discomfort.

VitaPost ProJoint Plus


ProJoint Plus, designed by VitaPost, is an excellent joint product that uses enough chondroitin and glucosamine to improve cartilage strength. According to various studies, turmeric is among the globally popular anti-inflammatory compounds that help reduce swelling, stiffness and decrease joint pain.

Other powerful ingredients like methionine, bromelain, and quercetin are well-known for their ability to repair joints’ damages and decrease inflammation and pain.

Whether you’re an athlete or runner, or just a person with arthritis, VitaPost ProJoint Plus has all it takes to reduce swelling and joint discomfort quickly.

Joint Support + by Nuzena


Nuzena is a relatively new manufacturer in the supplement industry, but its joint supplement is making waves already. Joint Support + consists of a whopping 150mg of chondroitin and 1500mg of glucosamine – the two most scientifically backed supplement ingredients to relieve inflammation and improve joint health.

In addition to that, the supplement also includes additional ingredients such as Boswellia, bromelain, and turmeric. These ingredients offer pain relief and extra support. Once Nuzena becomes more widely known, we can gather more customers’ evidence, and the products will likely quickly be listed among our top 3 joint supplements.

MoveMD by 1MD


MoveMD from 1MD is a fantastic advanced joint support product that reduces joint discomfort. The product consists of three clinically studied compounds: UC-II Undenatured type II collagen, ApresFlex Boswellia Serrata, and Zanthin Natural Astaxanthin.

These three compounds have been proven to remove joint inflammation, improve mobility, and decrease joint discomfort. Though it’s not as potent as other supplements on our list, MoveMD is an excellent supplement, especially if you have chronic joint pain that hinders your mobility.

Universal Nutrition Animal Flex


Unlike other conventional joint supplements, Universal Nutrition Animal Flex was developed with bodybuilders and elite athletes in mind. In addition to traditional ingredients like glucosamine and chondroitin, it also has various minerals and vitamins such as Vitamin E, Vitamin A, selenium, zinc, and many more.

If you have traditional joint pain problems due to old age or arthritis, the Animal Flex joint supplement might not be the best option. However, if you’re an elite athlete or bodybuilder and haven’t found traditional supplements worthwhile, then Animal Flex is worth a try.

Zenwise Advanced Strength Joint Support


Zenwise Advanced Strength Joint Support is an incredible joint product encompassing all the bases. The product contains 500 mg of glucosamine alongside hyaluronic acid, MSM, and chondroitin, popular primary ingredients in most joint supplements.

In addition to these primary ingredients, the product also includes additional inflammatory compounds like curcumin and Boswellia. These ingredients make Zenwise a better option if you have issues with swelling and redness in your joints. What’s more, you can purchase the product on Amazon. So we recommend that you become an Amazon Prime member to get free two-day shipping as an additional bonus.

Vimerson Health Glucosamine Chondroitin Turmeric MSM & Boswellia


Vimerson Health Glucosamine Chondroitin Turmeric MSM & Boswellia is the last supplement on our best joint supplement list. The product contains the usual dosage of the significant three ingredients – MSM, chondroitin, and glucosamine.

Additionally, the product includes Boswellia, bromelain, and turmeric ingredients. So if the three most popular components are not working on their own, the additional anti-inflammatory compounds may pick up the slack.

Schiff Move Free Joint Health


Schiff Move Free is among the most popular joint supplements. If you’re familiar with the supplement industry, you would have come across any of the many advertisements for Move Free. Schiff has been in the business for quite some time, and Move Free is one of its favored products.

The product has all you require in a joint supplement – MSM, hyaluronic acid, chondroitin, and glucosamine. The most impressive thing is that Move Free was designed very closely with clinical studies, so you know you’re purchasing an effective and reliable joint product. While it’s still not our best product, it’s an incredible supplement that can help enhance mobility and reduce joint discomfort.

Who needs a Joint Supplement?

A joint supplement is seen as a supplement used by adults and people with inflammatory problems like arthritis. However, the reality is that everyone can enjoy the benefits of joint supplements. The reason is that joint supplement helps to reduce inflammation that causes swelling and joint pain. The supplement also offers the body the needed nutrients to slow down the breakdown of cartilage or even reverse some damages.

Joint products are highly beneficial in adults with arthritis. Perhaps less specific is whether these products can be used as a preventive measure by healthy adults looking to avoid joint discomfort in the future.

Runners, athletes, and people with intensive labor careers might also benefit from using these products. Labor-intensive activities, weightlifting, and running can cause extreme stress on our joints, resulting in their breakdown. Joint supplements are good products to help us reduce or prevent the risk of inflammation and strengthen the cartilage for healthy, pain-free joints. Runners, athletes, and people with intensively active careers might benefit from using these products.

Factors Considered in our Ranking

Before determining which supplement is the best fit to include in our ranking, we considered some factors. Some of the primary ones include:

The ingredient formula

The first thing we considered in our rankings was the ingredient formula. The three most popular ingredients include chondroitin, MSM, and glucosamine. We ensure that these supplements contain ingredients that are scientifically studied with evidence to reduce inflammation and joint discomfort. Other ingredients considered are collagen and hyaluronic acid since they enhance joint strength.


Once we check the ingredient formula, we ensure that the product contains the correct dose. Compounds like MSM and glucosamine have been intensely studied since the global rate of arthritis continues to rise. So we exclude any supplements that do not contain the correct dose of ingredients as used in clinical studies. Aside from that, we did not include products with very high dosages.

Customers Reviews

Even if a supplement contains the required ingredient formula in the correct dosage, we still need to check if it satisfies customers’ expectations. So we ensure that we look at what experience an average customer has and choose products with the best overall experience.

However, we came across companies with paid or fake customer feedback, so we are acutely aware of that in our assessments.

Advantages of Joint Supplements

Joint pain or discomfort is among the common health issues affecting almost anybody, irrespective of age. Because of that, the number of clinical studies on joint supplements is impressive.

Nowadays, it’s evident that joint products can have several benefits if formulated in the correct dosage. Some of the advantages of joint supplements include:

Joint products can address the leading cause of pain and inflammation

Inflammation and pain in the joints are mainly caused by weakening joint fusion, swollen joints, worn joint cartilage, and bone erosion. As discussed earlier, if your joint space becomes smaller, the cartilage weakens, and the bones will start to rub against each other when you walk. This will increase joint inflammation and wear down the bone to cause severe pain. Additionally, it can build up fluids, causing swellings in the joint.

Joint supplements consist of anti-inflammatory compounds alongside compounds that can repair cartilage. You might still experience smaller amounts of pain in your joints. Still, joint products have been proven to significantly support mobility and decrease pain by attending to the leading cause of joint problems.

Joint supplements may slow cartilage breakdown and arthritis

At some point in life, almost everybody will experience arthritis. This health issue is caused by the breakdown of cartilage, which can lead to severe inflammation, redness, and swelling. Most joint supplements contain glucosamine and chondroitin, which have been clinically proven to be potent at slowing down the progress of arthritis. In a research study, patients given a dose of 400mg of chondroitin and 500mg of glucosamine experienced a significant reduction in overall inflammation, swelling, and pain within a week compared to a placebo.

When you use these ingredients together, the effect is multiplied. Another bit of research using both ingredients discovered a notable impact on the narrowing of joint space in arthritis – an issue that causes pain and inflammation. Most importantly, glucosamine and chondroitin will decelerate the narrowing of joint space. This further stops the arthritis process.

Joint products can help to lubricate joints

Another benefit of joint supplements is the lubrication of the joints. These supplements contain an ingredient known as hyaluronic acid, which can hydrate and moisturize the skin. So most manufacturers add this ingredient to their products because it helps to lubricate joints to reduce rubbing and joint tension.

Even small amounts of hyaluronic acid have several advantages. Studies have discovered that hyaluronic acid can help raise DNA synthesis in collagen. Additionally, it can enhance the collagen matrix with the joint cartilage, moisturizing the joint to decrease pain and tension.

The collagen effect

Collagen is considered among the body’s building blocks because it’s present in almost everybody. Your teeth, skin, joints, bones all have cartilage present in them. Joint products can repair torn cartilage and enhance collagen levels:

Supplementing collagen to support joint health is an incredible thing. Several studies have discovered that increasing collagen can help to enhance your joints and bone’s strength. Hydrolyzed collagen is among the more famous forms of collagen, and it’s highly beneficial towards joint cartilage growth and bone density. It’s even helpful to bone cartilage that is damaged or worn down.

Safety & Side Effects of Joint Supplements

Ingredients like chondroitin and glucosamine present in most joint supplements are the most studied compounds in history. Their safety is assured, and they’re considered very low-risk. The likelihood of complications is practically non-existent.

Studies have shown that glucosamine is safe for adults with allergies to seafood (glucosamine can be obtained from shrimp). Some medical practitioners won’t recommend glucosamine to adults with shellfish allergies. However, studies have been positive for adults with such allergies.

In addition, some herbal extracts with relatively fewer studies seem to be highly safe to use. MSM, turmeric, quercetin, and bromelain are popularly known to be safe and should not cause any serious risk for your health.

Dosing in joint supplements isn’t as essential as other supplements regarding safety. The reason is that the body well tolerates the ingredients within these supplements. Nevertheless, the dosage is still vital for better effectiveness.

Additionally, most studies have administered a dose of 500mg to 1000mg of chondroitin and glucosamine, usually with a ratio of 5 to 4 in that order. This is the perfect dosage, and clinical evidence supports the claim that these two ingredients are highly effective when used together. So you should probably stick with supplements with dosage within this range.

Joint Supplement FAQs

Q: What exactly are joint supplements?

A: Joint products are supplements developed to support and strengthen the cartilage and bones on your joints. These supplements are produced to decrease inflammation, joint discomfort, and swelling. It also promotes joint strength and mobility.

Unlike other medications, you can buy supplements over the counter. These supplements can be purchased online, or you can visit your local Wal-Mart and CVS and possibly find dozens of supplements.

Q: Can joint products work?

A: Several proofs from reviewed studies show that most compounds in joint products can help decrease joint inflammation and pain. The most globally studied compounds are MSM, glucosamine, and chondroitin.

Studies also suggest that these products can reduce inflammation in our joints with a reasonable level of reliability – especially for people with particular health problems like arthritis.

Another study has discovered that joint products can even restore collagen growth in damaged joints. This is something that wasn’t previously possible.

All in all, there’s a reasonable level of reliability when you use joint supplements. So people with joint discomfort have a great chance of enhancing mobility and decreasing joint pain after taking any of the products.

You should remember that joint products can’t perform miracles. So they won’t heal or fix the wear and tear from a long time of active living. Nevertheless, they can mitigate or even remove joint inflammation, relieve pain, and enhance your quality of living.

Q: How do joint supplements work?

A: Generally, joint products need to take a three-way approach to joint health. The product can help to remove joint inflammation, restore cartilage repair, and decrease joint discomfort.

Most top supplements on our list contain vital compounds that have been clinically proven to realize these goals. However, among these three goals, a joint product must help restore damaged cartilage because removing joint inflammation and pain is impossible without strengthening the joints.

More of the discomfort related to arthritis is caused by the grinding of bones around the joints. Stimulating cartilage growth and joint lubricating can reduce joint pain and prevent bone grinding. Some joint products also contain compounds that increase lubrication and restore cellular repair in our joints.

In some cases, joint products contain collagen to help repair cartilage by enhancing the presence of naturally generated collagen.

No matter the ingredient in your joint product, the supplement needs to attain these three goals we highlighted above – remove inflammation, increase joint repair and strength, and decrease joint pain.

Q: Are joint products that safe?

A: Most common compounds in joint products have been widely studied, and there’s been practically no presence of complications or severe health issues resulting from taking a joint supplement.

Glucosamine, hyaluronic acid, MSM, and chondroitin are all tolerated very well, with practically no reported occurrence of complications.

Other less popular herbal extracts might have complications; however, we noticed no complications from compounds like bromelain and turmeric.

Generally, we recommend that you follow the dose on the box and keep track of how you feel when taking a joint supplement. If you experience any side effects, stop the usage and contact your doctor to confirm if you have any condition influenced by any of the compounds in your joint product.

Q: Are there any other vitamins I can take for my joints?

A: Yes. There are other vitamins that you can take for your joints. Animal Flex is among the products with these additional vitamins.

Because inflammatory problems cause joint discomfort and arthritis, the essential vitamins for joint health are antioxidants and potent anti-inflammatories. Additionally, vitamins such as vitamin E and C are crucial for joint health.

Vitamin D is not technically an antioxidant. However, it’s essential to control the immune system’s response to inflammation. Also, the levels of Vitamin D have been connected to a lesser risk of arthritis in various studies. Though the direct association is unknown, it can also help to slow down the progression of arthritis.

Even though the connection between joint health and vitamin D is not that strong, people can still benefit from vitamin D – especially during the flu and cold season.

The Best Joint Supplements for 2021 Summary

The joint health product industry is among the scientifically studied and reliable aspects of the more extensive, wider supplement industry.

Though these supplements are not regulated like drugs, they should play a vital part in decreasing the effect of arthritis in several similar ways, but they can’t perform miracles.

If you’re suffering from constant pain, joint soreness, immobility, and inflammation, then a joint product may be the right supplement to consider. Studies have proven that chondroitin and glucosamine have positive effects on joint health.

Finding a joint product containing these ingredients (like the products on our list) will offer the best chance at removing joint inflammation, relieving pain, and enhancing your mobility.

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Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.